diff --git a/Misc/NEWS.d/next/Build/2025-02-07-21-20-21.gh-issue-129838.fkuiEc.rst b/Misc/NEWS.d/next/Build/2025-02-07-21-20-21.gh-issue-129838.fkuiEc.rst
new file mode 100644
index 00000000000000..958460249a65b6
--- /dev/null
+++ b/Misc/NEWS.d/next/Build/2025-02-07-21-20-21.gh-issue-129838.fkuiEc.rst
@@ -0,0 +1,2 @@
+Don't redefine ``_Py_NO_SANITIZE_UNDEFINED`` when compiling with a recent
+GCC version and undefined sanitizer enabled.
diff --git a/Modules/faulthandler.c b/Modules/faulthandler.c
index 2d16028a5232d0..d2ff555434cfc1 100644
--- a/Modules/faulthandler.c
+++ b/Modules/faulthandler.c
@@ -34,14 +34,15 @@
 #define PUTS(fd, str) (void)_Py_write_noraise(fd, str, strlen(str))
 
 
-// clang uses __attribute__((no_sanitize("undefined")))
-// GCC 4.9+ uses __attribute__((no_sanitize_undefined))
-#if defined(__has_feature)  // Clang
+// Clang and GCC 9.0+ use __attribute__((no_sanitize("undefined")))
+#if defined(__has_feature)
 #  if __has_feature(undefined_behavior_sanitizer)
 #    define _Py_NO_SANITIZE_UNDEFINED __attribute__((no_sanitize("undefined")))
 #  endif
 #endif
-#if defined(__GNUC__) \
+
+// GCC 4.9+ uses __attribute__((no_sanitize_undefined))
+#if !defined(_Py_NO_SANITIZE_UNDEFINED) && defined(__GNUC__) \
     && ((__GNUC__ >= 5) || (__GNUC__ == 4) && (__GNUC_MINOR__ >= 9))
 #  define _Py_NO_SANITIZE_UNDEFINED __attribute__((no_sanitize_undefined))
 #endif