diff --git a/Misc/NEWS.d/next/Build/2023-05-04-10-56-14.gh-issue-104106.-W9BJS.rst b/Misc/NEWS.d/next/Build/2023-05-04-10-56-14.gh-issue-104106.-W9BJS.rst
new file mode 100644
index 00000000000000..900e5bd61d6033
--- /dev/null
+++ b/Misc/NEWS.d/next/Build/2023-05-04-10-56-14.gh-issue-104106.-W9BJS.rst
@@ -0,0 +1 @@
+Add gcc fallback of mkfifoat/mknodat for macOS. Patch by Dong-hee Na.
diff --git a/Modules/posixmodule.c b/Modules/posixmodule.c
index 613b86f09c9eaf..c825aeedcf085d 100644
--- a/Modules/posixmodule.c
+++ b/Modules/posixmodule.c
@@ -169,6 +169,14 @@
 #    define HAVE_PWRITEV_RUNTIME (pwritev != NULL)
 #  endif
 
+#  ifdef HAVE_MKFIFOAT
+#    define HAVE_MKFIFOAT_RUNTIME (mkfifoat != NULL)
+#  endif
+
+#  ifdef HAVE_MKNODAT
+#    define HAVE_MKNODAT_RUNTIME (mknodat != NULL)
+#  endif
+
 #endif
 
 #ifdef HAVE_FUTIMESAT